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Message: <blockquote data-quote="Professor" data-source="post: 42920" data-attributes="member: 202"><h3>Why misinterpretation of electron micrographs in SARS-CoV-2-infected tissue goes viral</h3>  .  .  .  ultrastructural details in autopsy tissues have been misinterpreted as coronavirus particles in recent papers. Bradley and colleagues described “coronavirus-like particles” in autopsy specimens of the “respiratory system, kidney, and gastrointestinal tract”, and in a case report Dolhnikoff and colleagues described “viral particles” in “different cell types of cardiac tissue” of a deceased child. However, the images in these publications show putative virus particles that lack sufficient ultrastructure for an unambiguous identification as virus. - Hoax, they're not viruses at all<img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite10" alt=":oops:" title="Oops!    :oops:" loading="lazy" data-shortname=":oops:" /> .  .  .  findings, described by Tavazzi and colleagues,of “viral particles” in interstitial cells, which are clearly non-viral structures, such as coated vesicles. Furthermore, Bradley and colleagues quoted publications as a reference for their virus particle identification, which, in our opinion, both identified non-coronavirus structures as coronavirus particles,<img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite10" alt=":oops:" title="Oops!    :oops:" loading="lazy" data-shortname=":oops:" />With interest we follow the publications that show the presence of putative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by electron microscopy (EM) in patient tissues and the debate about these results, - Good, let's see<img class="smilie smilie--emoji" loading="lazy" alt="🧐" title="Face with monocle    :face_with_monocle:" src="https://cdn.jsdelivr.net/joypixels/assets/6.5/png/unicode/64/1f9d0.png" data-shortname=":face_with_monocle:" /> .  .  .[ATTACH=full]2099[/ATTACH]Now, the following is the kicker in regard to the blinding science sourced by twits as evidence .  .  . .  .  . As diagnostic EM requires both specialised staff and expensive equipment, and has been replaced by other methods (eg, immunohistochemistry) in several fields of application, its use has been in decline in the past decades, resulting in irreversible loss of expertise that now becomes dramatically overt during the SARS-CoV-2 pandemic. This dilemma of diagnostic EM should alarm us all, as misleading information on the presence of SARS-CoV-2 in tissue has already made its way into the scientific literature and seems to be perpetuated. <img class="smilie smilie--emoji" loading="lazy" alt="😲" title="Astonished face    :astonished:" src="https://cdn.jsdelivr.net/joypixels/assets/6.5/png/unicode/64/1f632.png" data-shortname=":astonished:" />We declare no competing interests. [URL unfurl="true"]https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32079-1/fulltext[/URL]</blockquote>

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