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🦠 Covid 19 Vaccine Thread 💉
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<blockquote data-quote="A Man Called Charolais" data-source="post: 69010"><p style="text-align: center">[MEDIA=twitter]1735552077282128382[/MEDIA]</p> <p style="text-align: center"></p> <p style="text-align: center"></p><p>This frameshifting issue is still getting airtime. The article below is a much more explanatory one. Apparently it's just a problem with Pfizer so far but AstraZeneca used a different technology - no mention of Moderna.</p><p style="text-align: center"></p><p>'While most naturally occurring mRNA contains uridine, the Pfizer mRNA vaccines use N1-methylpseudouridine. This makes the mRNA sequence hardier and less prone to breakdown by the immune system. Pfizer’s opting for less commonly occurring mRNA bases is also why some scientists call the mRNA vaccines modified RNA, or modRNA.</p><p></p><p>...</p><p></p><p>Apart from frameshift errors, the N1-methylpseudouridine modification can also slow down and interrupt mRNA translation to protein, potentially leading to shorter-than-expected protein sequences.</p><p></p><p>"Under ideal circumstances, ribosomes translate the vaccine mRNA into the S [spike] protein ... If the cellular machine (ribosomes) 'detect' the difference [between normal uridine and N1-methylpseudouridine], it can result in stalling or mistranslation," Dr. Adonis Sfera, assistant clinical professor of medicine at Loma Linda University, wrote to The Epoch Times via email.</p><p></p><p>In the study, the researchers first inoculated mice with both Pfizer and AstraZeneca vaccines. They found that Pfizer vaccines were significantly more likely to produce frameshifted proteins.</p><p></p><p>Researchers then compared vaccine inoculations in humans, comparing 21 participants who took the Pfizer vaccine to 20 who took the AstraZeneca vaccine. None of the AstraZeneca vaccinees had an immune reaction to proteins made from mistakes in translation, but around one-third of the Pfizer vaccinees did.</p><p></p><p>...</p><p></p><p>Additionally, some health experts are concerned that these unique proteins may increase a person’s risk of developing autoimmune disorders.</p><p></p><p>Molecular biologist professor Vladimir Uversky, PhD, from the University of South Florida and physician Dr. Alberto Rubio-Casillas concluded that autoimmunity may occur if immune cells start attacking cells producing these aberrant proteins.</p><p></p><p>"A mistranslated protein can [also] resemble a human protein and trigger antibody formation," Dr. Sfera added.</p><p></p><p>Autoimmunity occurs when the immune system attacks self-tissues. It can occur for many years before symptoms manifest.</p><p></p><p>Study findings by immunologist Aristo Vojdani suggest that spike proteins have the potential to cause cross-reactions—meaning the body accidentally targets self-tissue in a fight against other pathogens—with over 20 different human tissues, as they share structural similarities with human proteins.</p><p></p><p>The production of these aberrant proteins and peptides may also increase a person’s risks of cancer, Mr. Uversky and Dr. Rubio-Casillas added in an email to The Epoch Times.</p><p></p><p>Melanoma cells have been shown to induce frameshifted proteins to escape immune detection.</p><p></p><p>“In our opinion, there is a possibility that during the translation of mRNA from COVID-19 vaccines, the aberrant proteins generated during frameshifting could activate survival mechanisms mimicking those developed by cancer cells to escape immune surveillance,” the two added.'</p><p></p><p><a href="https://www.zerohedge.com/political/pfizer-mrna-vaccine-makes-aberrant-proteins-experts-concerned-about-autoimmunity-events" target="_blank">Pfizer mRNA Vaccine Makes 'Aberrant Proteins', Experts Concerned About Autoimmunity Events - ZeroHedge</a></p><p></p><p></p><p>I remember wild eyed remarks about the vaccines giving you cancer back in 2021. Maybe not so eccentric after all.</p></blockquote><p></p>
[QUOTE="A Man Called Charolais, post: 69010"] [CENTER][MEDIA=twitter]1735552077282128382[/MEDIA] [/CENTER] This frameshifting issue is still getting airtime. The article below is a much more explanatory one. Apparently it's just a problem with Pfizer so far but AstraZeneca used a different technology - no mention of Moderna. [CENTER][/CENTER] 'While most naturally occurring mRNA contains uridine, the Pfizer mRNA vaccines use N1-methylpseudouridine. This makes the mRNA sequence hardier and less prone to breakdown by the immune system. Pfizer’s opting for less commonly occurring mRNA bases is also why some scientists call the mRNA vaccines modified RNA, or modRNA. ... Apart from frameshift errors, the N1-methylpseudouridine modification can also slow down and interrupt mRNA translation to protein, potentially leading to shorter-than-expected protein sequences. "Under ideal circumstances, ribosomes translate the vaccine mRNA into the S [spike] protein ... If the cellular machine (ribosomes) 'detect' the difference [between normal uridine and N1-methylpseudouridine], it can result in stalling or mistranslation," Dr. Adonis Sfera, assistant clinical professor of medicine at Loma Linda University, wrote to The Epoch Times via email. In the study, the researchers first inoculated mice with both Pfizer and AstraZeneca vaccines. They found that Pfizer vaccines were significantly more likely to produce frameshifted proteins. Researchers then compared vaccine inoculations in humans, comparing 21 participants who took the Pfizer vaccine to 20 who took the AstraZeneca vaccine. None of the AstraZeneca vaccinees had an immune reaction to proteins made from mistakes in translation, but around one-third of the Pfizer vaccinees did. ... Additionally, some health experts are concerned that these unique proteins may increase a person’s risk of developing autoimmune disorders. Molecular biologist professor Vladimir Uversky, PhD, from the University of South Florida and physician Dr. Alberto Rubio-Casillas concluded that autoimmunity may occur if immune cells start attacking cells producing these aberrant proteins. "A mistranslated protein can [also] resemble a human protein and trigger antibody formation," Dr. Sfera added. Autoimmunity occurs when the immune system attacks self-tissues. It can occur for many years before symptoms manifest. Study findings by immunologist Aristo Vojdani suggest that spike proteins have the potential to cause cross-reactions—meaning the body accidentally targets self-tissue in a fight against other pathogens—with over 20 different human tissues, as they share structural similarities with human proteins. The production of these aberrant proteins and peptides may also increase a person’s risks of cancer, Mr. Uversky and Dr. Rubio-Casillas added in an email to The Epoch Times. Melanoma cells have been shown to induce frameshifted proteins to escape immune detection. “In our opinion, there is a possibility that during the translation of mRNA from COVID-19 vaccines, the aberrant proteins generated during frameshifting could activate survival mechanisms mimicking those developed by cancer cells to escape immune surveillance,” the two added.' [URL='https://www.zerohedge.com/political/pfizer-mrna-vaccine-makes-aberrant-proteins-experts-concerned-about-autoimmunity-events']Pfizer mRNA Vaccine Makes 'Aberrant Proteins', Experts Concerned About Autoimmunity Events - ZeroHedge[/URL] I remember wild eyed remarks about the vaccines giving you cancer back in 2021. Maybe not so eccentric after all. [/QUOTE]
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