Reply to thread

Message: <blockquote data-quote="Tiger" data-source="post: 125083" data-attributes="member: 353">[USER=121]@Myles O'Reilly[/USER], this video should be right up your street. It’s an hour and twenty two minutes long and choc of complex scientific jargon. <img class="smilie smilie--emoji" loading="lazy" alt="👍" title="Thumbs up    :thumbsup:" src="https://cdn.jsdelivr.net/joypixels/assets/6.5/png/unicode/64/1f44d.png" data-shortname=":thumbsup:" />[MEDIA=youtube]DT0TP_Ng4gA[/MEDIA]<a href="https://youtu.be/DT0TP_Ng4gA?feature=shared" target="_blank">View: https://youtu.be/DT0TP_Ng4gA?feature=shared</a>Denis Noble is a distinguished British physiologist and systems biologist, renowned for his pioneering contributions to cardiac physiology and evolutionary biology. In 1960, he developed the first mathematical model of the heart's electrical activity, which became a cornerstone of computational biology. A Fellow of the Royal Society and a Commander of the Order of the British Empire, Noble has served as President of the International Union of Physiological Sciences and received multiple honorary doctorates. As a leading advocate for systems biology, he challenges reductionist views, including the central dogma of molecular biology, emphasizing the importance of feedback mechanisms and epigenetics. His influential book The Music of Life and his critiques of gene-centric evolution have reshaped debates on biological complexity and evolution.In this video he challenges the traditional gene-centric view of evolution, notably popularized by Richard Dawkins in "The Selfish Gene." Noble argues that this perspective is overly reductionist and doesn't account for the complex interactions within biological systems. He emphasizes the importance of systems biology, which considers the intricate networks of genes, proteins, cells, and their environments, suggesting that understanding these interactions is crucial for a comprehensive grasp of evolutionary processes.Noble also critiques the central dogma of molecular biology—the idea that genetic information flows in a linear manner from DNA to RNA to proteins. He presents evidence of feedback mechanisms and epigenetic factors that can influence gene expression and inheritance, indicating a more dynamic and bidirectional flow of information. This perspective challenges the traditional view that genetic information is solely passed down through DNA sequences, highlighting the role of epigenetic modifications and environmental interactions in evolution.Furthermore, Noble discusses the Weismann barrier, which posits a strict separation between germ cells (responsible for reproduction) and somatic cells (constituting the body), suggesting that changes in somatic cells don't affect the germ line. He argues that this barrier is not absolute, pointing to evidence that environmental factors and epigenetic changes in somatic cells can influence the germ line, thereby affecting evolutionary outcomes.In summary, Noble advocates for a more integrative approach to biology, one that moves beyond the gene-centric view to incorporate the complexities of biological systems, epigenetic factors, and environmental interactions. This broader perspective aims to provide a more comprehensive understanding of the mechanisms driving biological developments.</blockquote>

Name

Verification: Does Doxxie know his real father.

Latest Threads

A Million Views.
- Started by Declan
- Saturday at 10:54 PM
- Replies: 12
Public Chat and Announcements
An Open Letter to SwordOfStZip
- Started by AN2
- Oct 11, 2025
- Replies: 12
Public Chat and Announcements
athletics
- Started by céline
- Oct 8, 2025
- Replies: 4
Public Chat and Announcements
S
The real agenda in this Presidential Election?
- Started by scolairebocht
- Oct 6, 2025
- Replies: 11
Scholairebochts Blog.
J
Varadkar "confronted by far right" while walking down street inDublin
- Started by Jay Homer Simpson
- Oct 2, 2025
- Replies: 6
Public Chat and Announcements

Popular Threads

Ukraine.
- Started by Declan
- Feb 21, 2022
- Replies: 15K
World at War
US Politics.
- Started by jpc
- Nov 7, 2022
- Replies: 6K
USA
Mass Migration to Ireland & Europe
- Started by Anderson
- Feb 26, 2023
- Replies: 5K
Nationalist Politics
C
🦠 Covid 19 Vaccine Thread 💉
- Started by Charlene
- Sep 14, 2021
- Replies: 3K
Health
General Chat in The Marcus Lounge.
- Started by Declan
- Dec 30, 2024
- Replies: 3K
Public Chat and Announcements
The Climate Change scam
- Started by Anderson
- Jul 29, 2022
- Replies: 2K
Climate Change