By the way Khamenei was against nuclear weapons, now with him gone...
Anyway its obviously descended into a pounding match between the US and Israel v. Iran, much like the former conflict, with the former crisscrossing Iranian airspace at will and taking out targets via their airforce and missiles from their naval assets while Iran is reponding with drones and missiles, initially with poorish quality of both and without a lot of success.
Initially you could say it was all US/Israel because they killed the Supreme leader and a lot of other highups, because the Iranian navy and airforce seem to be already sunk, but I think, at this point anyway, it might be reverting back to Iran a little, because:
Looking at it from the point of view of attacks on Iran:
1. It is after all a huge country with many massive but spread out cities and enormous infrastructure. You just cannot cripple a country of that size very quickly or easily.
2. The Iranian population and army might be used to, a little anyway, these attacks and privations in general, because they have been under sanctions for so long.
3. The US/Israel might be caught between two stools in their attacks anyway, because they have high hopes of an Iranian uprising against their government, and hence widescale attacks, which would lead to widespread civilian casualties, could be counter productive for them.
Now look at the attacks against Israel:
1. Israel is a very small country, with their population packed into high rise units in only a few cities. Say for example if you wanted to knock out power supply infrastructure or ports or water desalination or transport facilities, there are only a few key targets you need to hit, totally unlike the situation in Iran.
2. The Israeli population, in this first world country with all conveniences etc might not be ready for all of this, unlike Iranians under sanctions for so long. Some might panic and flee now.
3. There is no love lost towards the Israeli population by the Iranians, now that they assassinated the leaders, and anyway there are a lot of others dissolusioned with Israel right now, so no holds barred in any attacks.
So even exclusive of this talk of US and Israeli missiles running out, I think it is swinging towards Iran right now.